Pre-emptive analgesia efficacy of piroxicam versus tramadol in oral surgery
Muthuluri Tejdeep, Chandrupatla Siddardha Gowtam, Rajan Ritesh, Reddy Viveka V., Jhawar Dinesh K., Potturi Abhinand,
소속 상세정보
( Muthuluri Tejdeep ) - SVS Institute of Medical and Dental Sciences Department of Oral and Maxillofacial Surgery
( Chandrupatla Siddardha Gowtam ) - Ibn Sina Foundation Public Health Dentist
( Rajan Ritesh ) - SVS Institute of Medical and Dental Sciences Department of Oral and Maxillofacial Surgery
( Reddy Viveka V. ) - SVS Institute of Medical and Dental Sciences Department of Oral and Maxillofacial Surgery
( Jhawar Dinesh K. ) - SVS Institute of Medical and Dental Sciences Department of Oral and Maxillofacial Surgery
( Potturi Abhinand ) - SVS Institute of Medical and Dental Sciences Department of Oral and Maxillofacial Surgery
Abstract
Background: This double-blind randomized controlled trial (RCT) was conducted to evaluate the pre-emptive analgesia and anti-inflammatory efficacy of piroxicam compared with tramadol in patients undergoing oral surgery.
Methods: Seventy-eight patients who required extraction of impacted mandibular third molars were randomized into three treatment groups of 26 patients each: group I received 100 mg of tramadol, group II received 20 mg of piroxicam, and group III received a placebo. Drugs were administered intramuscularly 30 min prior to the extraction procedure.
Results: Pain intensity, time to first analgesic administration, total analgesic consumption, facial edema, and trismus were the outcomes of interest. The group receiving 20 mg of piroxicam showed significantly lower pain intensity, increased time to first analgesic, and reduced edema from preoperative to postoperative day seven than those in the tramadol and placebo groups.
Conclusion: The findings of this study showed that piroxicam had significant pain relief efficacy after third molar surgery compared with that in tramadol.
키워드
Piroxicam; Preemptive Analgesia; Third Molar; Tooth Extraction; Tramadol
원문 및 링크아웃 정보
등재저널 정보